AIMS AND OBJECTIVES: -

1) To study the efficacy of homoeopathic constitutional medicine in the management of benign prostatic hypertrophy.

PROSTATE - INTRODUCTION

The Prostate (Prostata; Prostate Gland) is an organ linked inextricably with the endocrine system. During the development of the prostate, epithelium and mesenchyma are under the control of testicular androgens, and interact to form an organised secretory organ. Furthermore, many of the disease processes are attributed to, and therapies aimed at the manipulation of, the endocrine system. The gland resides in the true anatomical pelvis and forms the most proximal aspect of the urethra. It has been stated that the prostate gland is the male organ most commonly afflicted with either benign or malignant neoplasm.

MATERIALS AND METHODS

The study was conducted in male patients attending our clinics of Homeocare International between the age group of 50- 75 years of during the period 2007 to 2009.

Samples: Samples of 400 cases diagnosed, as benign prostatic hypertrophy based on ultrasonographic report were selected. All the patients selected were already diagnosed as benign prostatic hypertrophy before conducting the study. Aim of the study was to access the efficiency of homeopathic constitutional Medicines in the Management of benign prostatic hypertrophy.

Diagnostic Points

1. Symptoms of incomplete emptying, frequency, intermittency, urgency, weak stream and straining.
2. Positive ultrasonogram finding.
3. Digital rectal examination.
Inclusion criteria
1. 400 well-diagnosed benign prostatic hypertrophy cases, confirmed on the basis of clinical features along with the positive ultrasonographic reports were randomly selected.
2. Age group 50-75 yrs.
3. Purely benign cases.

Exclusion Criteria

1. Cases with high serum PSA levels
2. Cases with DRE findings suggestive of C.A Prostate
3. Case that do not fulfill the diagnostic criteria

Methods

History of illness was elicited in an elaborate manner as per the principles of Homeopathy. Case history was recorded in detail. All the symptoms including subjective and objective were considered. After taking the totality of symptoms, evaluation of the cases according to Kent’s Method was done to find out the similimum. Individualizing symptoms were given more importance. Remedies were selected based on individual constitutional peculiarities. When the totality of symptoms underwent considerable changes, case was retaken and the second medicine was given based on the symptom similarity. In between two doses of medication, placebo was administered liberally.

Homoeopathic principles and single medicine, similar remedy and minimum dose were strictly adhered.

All the patients were advised not to take other medications, internally or externally, strong and spicy foods, coffee, tea, condiments and other food items supposed to be of possessing medicinal value during the study period.

OBSERVATION AND RESULTS

Demographic Data
Classification of the patients according to age.

Age group

Number of people

PERCENTAGE (%)

50-55

132

33
56-60
120
30

61-65

64

16
66-70
68
17
71-75
16
4

Table - Classification of patients according to the age.

Patients coming in the age group 50- 75 were included in the study. From the above diagram it is clear that the occurrence of benign prostatic hypertrophy were more among age group 50- 55. Next significant age group was 56-60.

Arnica

13

Calc carb

27

Carcinosin

13

Causticum

27

Conium mac

27

Digitalis

13
Lycopodium
27
Medorrhinum
40
Natrum sulph
13
Nitric acid
13
Pulsatilla
27
Selenium
13
Staphysagria
27
Sulphur
27
Thuja
93

Table- Order of effective medicine

Among 400 cases medicine indicated most of times is Thuja- 24%. Then Medorrhinum 10%, followed by Calc carb, Causticum, Conium mac, Lycopodium, Pulsatilla, Staphysagria, Sulphur 7% each and Arnica, Carcinocin, Digitalis, Natrum sulph, Nit ac, Selenium 4%each.

Incomplete emptying

101

Frequency

100

Intermittency

83

Urgency

95

Weak stream

89

Straining

88
Nocturia
88

From the analysis of the IPSS sheet of 400 cases the above pattern of symptom predominance was noted.

DISCUSSION

To arrive at a valid conclusion, we are indebted to discuss some of the findings that have evolved out of this study. The result is exclusively based on the observation and result presented in former section.

1. Age incidence: The maximum incidence was in the age group 50 -55. The next greater prevalence was in age group 56 - 60.
2. Distribution of patients according to socio economic class:-In this study conducted, benign prostatic hypertrophy is found more among middle class (66.7%)
3. Distribution of patients according to associate complaints:-In this study conducted benign prostatic hypertrophy is found to be associated with infiltration and deposition of various organs and tissues which confirms the sycotic predominance in BHP patients. In USG renal calculi, renal cortical cyst and fatty liver and in analysis of case records warts, hydrogenoid constitutions etc which are all pathologies having base on sycotic miasm are found associated with BHP.
4. Economic aspect: Only 13% of the total patients were in the poor economic class. Majority belonged to middle and higher class, showing the more prevalence of disease among the middle and higher class due to their life style.
5. Distribution of clinical features: Among the symptoms given in the IPSS sheet, the predominance of the symptoms were noted as follows, Incomplete emptying of bladder (16%), increased frequency of micturition (16%), urgency (15%), weak stream (14%), straining (13%), nocturia (13%) intermittency (13%).
6. Evaluation of change in disease criteria: The comparison of the USG measurement of prostate and the IPS Score before and after treatment showed statistically significant result.
7. Medicines used: Among 400 cases medicine indicated most of times is Thuja- 24%. Then Medorrhinum 10%, followed by Calc carb, Causticum, Conium mac, Lycopodium, Pulsatilla, Staphysagria, Sulphur 7% each and Arnica, Carcinocin, Digitalis, Natrum sulph, Nit ac, Selenium 4%each.

CONCLUSION

From the evaluation of results obtained after the statistical analysis of the benign prostatic hypertrophy cases, it is obvious that sycotic miasm shows a pre-dominance of 57.67%.
Anti-sycotic medicines like Thuja, Medorrhinum, Staphysagria, Causticum, Conium mac were found to be effective. Also trimiasmatic medicines like Calcarea carb, Lycopodium also found to be effective.
By anti-miasmatic constitutional treatment it is found that the enlargement of prostate can be retarded or prevented.
It is found that the comparison of the USG measurement of prostate and the IPS Score before and after treatment showed statistically significant result. It can also be claimed that Homoeopathy is safe, simple, less expensive and more effective in treating benign prostatic hypertrophy cases. Unnecessary surgery can be avoided.

Homoeopathy as a system of medical treatment has a philosophy of its own and its therapeutics are based on certain fundamental principles.

To conclude in Hahnemann’s words “He, who has had as many opportunities as I to make observations,… he, who is induced by his desire for the welfare of his fellow beings to think and act for himself, he, who like myself feels hatred for the prejudices and preferences for old or new, or, generally speaking, for any kind of recognition or great name, and he, who eagerly endeavours, as I myself have done, to act and to think independently…. he will see excellent results for his industry which is the greatest reward that a honest physician can expect”.

AIMS AND OBJECTIVES: -

1) To study the efficacy of homoeopathic constitutional medicine in the management of benign prostatic hypertrophy.

PROSTATE - INTRODUCTION

The Prostate (Prostata; Prostate Gland) is an organ linked inextricably with the endocrine system. During the development of the prostate, epithelium and mesenchyma are under the control of testicular androgens, and interact to form an organised secretory organ. Furthermore, many of the disease processes are attributed to, and therapies aimed at the manipulation of, the endocrine system. The gland resides in the true anatomical pelvis and forms the most proximal aspect of the urethra. It has been stated that the prostate gland is the male organ most commonly afflicted with either benign or malignant neoplasm.

MATERIALS AND METHODS

The study was conducted in male patients attending our clinics of Homeocare International between the age group of 50- 75 years of during the period 2007 to 2009.

Samples: Samples of 400 cases diagnosed, as benign prostatic hypertrophy based on ultrasonographic report were selected. All the patients selected were already diagnosed as benign prostatic hypertrophy before conducting the study. Aim of the study was to access the efficiency of homeopathic constitutional Medicines in the Management of benign prostatic hypertrophy.

Diagnostic Points

1. Symptoms of incomplete emptying, frequency, intermittency, urgency, weak stream and straining.
2. Positive ultrasonogram finding.
3. Digital rectal examination.
Inclusion criteria
1. 400 well-diagnosed benign prostatic hypertrophy cases, confirmed on the basis of clinical features along with the positive ultrasonographic reports were randomly selected.
2. Age group 50-75 yrs.
3. Purely benign cases.

Exclusion Criteria

1. Cases with high serum PSA levels
2. Cases with DRE findings suggestive of C.A Prostate
3. Case that do not fulfill the diagnostic criteria

Methods

History of illness was elicited in an elaborate manner as per the principles of Homeopathy. Case history was recorded in detail. All the symptoms including subjective and objective were considered. After taking the totality of symptoms, evaluation of the cases according to Kent’s Method was done to find out the similimum. Individualizing symptoms were given more importance. Remedies were selected based on individual constitutional peculiarities. When the totality of symptoms underwent considerable changes, case was retaken and the second medicine was given based on the symptom similarity. In between two doses of medication, placebo was administered liberally.

Homoeopathic principles and single medicine, similar remedy and minimum dose were strictly adhered.

All the patients were advised not to take other medications, internally or externally, strong and spicy foods, coffee, tea, condiments and other food items supposed to be of possessing medicinal value during the study period.

OBSERVATION AND RESULTS

Demographic Data
Classification of the patients according to age.

Age group

Number of people

PERCENTAGE (%)

50-55

132

33
56-60
120
30

61-65

64

16
66-70
68
17
71-75
16
4

Table - Classification of patients according to the age.

Patients coming in the age group 50- 75 were included in the study. From the above diagram it is clear that the occurrence of benign prostatic hypertrophy were more among age group 50- 55. Next significant age group was 56-60.

Arnica

13

Calc carb

27

Carcinosin

13

Causticum

27

Conium mac

27

Digitalis

13
Lycopodium
27
Medorrhinum
40
Natrum sulph
13
Nitric acid
13
Pulsatilla
27
Selenium
13
Staphysagria
27
Sulphur
27
Thuja
93

Table- Order of effective medicine

Among 400 cases medicine indicated most of times is Thuja- 24%. Then Medorrhinum 10%, followed by Calc carb, Causticum, Conium mac, Lycopodium, Pulsatilla, Staphysagria, Sulphur 7% each and Arnica, Carcinocin, Digitalis, Natrum sulph, Nit ac, Selenium 4%each.

Incomplete emptying

101

Frequency

100

Intermittency

83

Urgency

95

Weak stream

89

Straining

88
Nocturia
88

From the analysis of the IPSS sheet of 400 cases the above pattern of symptom predominance was noted.

DISCUSSION

To arrive at a valid conclusion, we are indebted to discuss some of the findings that have evolved out of this study. The result is exclusively based on the observation and result presented in former section.

1. Age incidence: The maximum incidence was in the age group 50 -55. The next greater prevalence was in age group 56 - 60.
2. Distribution of patients according to socio economic class:-In this study conducted, benign prostatic hypertrophy is found more among middle class (66.7%)
3. Distribution of patients according to associate complaints:-In this study conducted benign prostatic hypertrophy is found to be associated with infiltration and deposition of various organs and tissues which confirms the sycotic predominance in BHP patients. In USG renal calculi, renal cortical cyst and fatty liver and in analysis of case records warts, hydrogenoid constitutions etc which are all pathologies having base on sycotic miasm are found associated with BHP.
4. Economic aspect: Only 13% of the total patients were in the poor economic class. Majority belonged to middle and higher class, showing the more prevalence of disease among the middle and higher class due to their life style.
5. Distribution of clinical features: Among the symptoms given in the IPSS sheet, the predominance of the symptoms were noted as follows, Incomplete emptying of bladder (16%), increased frequency of micturition (16%), urgency (15%), weak stream (14%), straining (13%), nocturia (13%) intermittency (13%).
6. Evaluation of change in disease criteria: The comparison of the USG measurement of prostate and the IPS Score before and after treatment showed statistically significant result.
7. Medicines used: Among 400 cases medicine indicated most of times is Thuja- 24%. Then Medorrhinum 10%, followed by Calc carb, Causticum, Conium mac, Lycopodium, Pulsatilla, Staphysagria, Sulphur 7% each and Arnica, Carcinocin, Digitalis, Natrum sulph, Nit ac, Selenium 4%each.

CONCLUSION

From the evaluation of results obtained after the statistical analysis of the benign prostatic hypertrophy cases, it is obvious that sycotic miasm shows a pre-dominance of 57.67%.
Anti-sycotic medicines like Thuja, Medorrhinum, Staphysagria, Causticum, Conium mac were found to be effective. Also trimiasmatic medicines like Calcarea carb, Lycopodium also found to be effective.
By anti-miasmatic constitutional treatment it is found that the enlargement of prostate can be retarded or prevented.
It is found that the comparison of the USG measurement of prostate and the IPS Score before and after treatment showed statistically significant result. It can also be claimed that Homoeopathy is safe, simple, less expensive and more effective in treating benign prostatic hypertrophy cases. Unnecessary surgery can be avoided.

Homoeopathy as a system of medical treatment has a philosophy of its own and its therapeutics are based on certain fundamental principles.

To conclude in Hahnemann’s words “He, who has had as many opportunities as I to make observations,… he, who is induced by his desire for the welfare of his fellow beings to think and act for himself, he, who like myself feels hatred for the prejudices and preferences for old or new, or, generally speaking, for any kind of recognition or great name, and he, who eagerly endeavours, as I myself have done, to act and to think independently…. he will see excellent results for his industry which is the greatest reward that a honest physician can expect”.

Further to the “in house” clinical research done at Homeocare International, the vast experience of our team of doctors has come to a better understanding of the diseases and their effective treatments. We have reached a stage wherein precision of prescription is achieved in all the cases with “in-depth” study of vast number of cases with the support of dedicated team of doctors who does clinical research.

We are Pleased to inform you that our team of doctors has found success formulae to various illnesses to add much value to the patients’ quality of life through genome therapy / CT therapy that had enhanced our success rate in almost all the diseases. This feat is not achieved by any body so far in the field of homeopathy except Homeocare International. To feel the blend of ultimate quality of homeopathic treatment and technology, please contact / visit our nearest clinic. Homeocare International, the Leaders in world class Homeopathy… we care always……all ways.